Property Calculator
Physicochemical descriptors and drug-likeness rules for one molecule or a whole list. Everything is computed locally in your browser with RDKit; nothing is uploaded.
Input
Examples:
Files: a SMILES list (.smi/.txt/.csv, one molecule per line) or an SD file (.sdf/.mol). Lines starting with # are ignored.
Ketcher loads once (about 23 MB); it runs entirely in your browser.
Results
Enter one or more SMILES and press Calculate. Values follow RDKit conventions: cLogP is the Crippen estimate, TPSA is the Ertl topological polar surface area, HBD/HBA follow Lipinski’s N–H/O–H and N/O counts.